Cincinnati, OH · Est. 2000 · Formerly Queen City Angels
Smart Capital for Disruptive Startups
Intelligent investments that build sound businesses. The longest-established organized angel group in the Midwest — 215+ member investors who are much more than a source for money.
25 years · 123 companies funded · 375 investments · 215+ member investors
The Multiplier · 25 Years of Proof
Every dollar a member commits multiplies.
Over 25 years, QCA members have invested $128M of their own capital. That capital pulled in co-investors and follow-on funds — syndicating into more than $1B of total capital for our founders. A ~7.8× multiplier, proven across 375 investments.
$1 in → ~$8 of total capital for the founder. One QCA member dollar (solid) travels with roughly seven syndicated dollars (outlined). $128M → $1B+ = ~7.8×.
What the multiplier means for you
QCA members invest in your round
that check has historically helped rally $781,000 of total capital into companies like yours. ~7.8× leverage
Grounded in QCA’s real 25-year record: $128M of member capital → $1B+ syndicated, across 375 investments in 123 companies.
The Record
Plus: 215+ angel investors · 1,000+ entrepreneurs trained · 50,000+ member-hours contributed annually.
$128M invested, $1B+ syndicated across 375 investments in 123 companies over 25 years — QCA Ventures, Cincinnati.
Who We Are
Much more than a source for money.
“QCA Ventures is passionate about supporting entrepreneurs. Entrepreneurs drive the economy, solve problems, make lives better, create jobs and are QCA Ventures’ primary reason for being.”
Non-profit 501(c)(6) · 215+ former CEOs & foundersOur Values
- Respect & Integrity
- Contribute & Collaborate
- Education & Ongoing Counsel
- Purposeful & Knowledgeable
- Forward-Thinking & Success Driven
Where We Invest
Three verticals. Deep operator knowledge in each.
Information Technology
B2B SaaS, enterprise software and IoT — backed by members who built and ran software companies themselves.
02Life Sciences
Therapeutics, med-tech and healthcare platforms, diligenced by members with deep clinical and commercial experience.
03Advanced Materials
Advanced manufacturing and materials science — the industrial backbone of the Midwest, funded at the earliest stage.
Portfolio Index
123 companies funded. A selection:
- Alphyn Biologics
- 3-Bar Biologics
- Bert Thin Films
- Cloverleaf
- ContentStatus
- Convey
- Endosphere
- FenixPyre
- Guardian Medical
- Groupize
- HealthyRoster
- How’s Mom
- iCHOR
- Intelligent Mobile Support
- Ischemia Care
- Kuro Therapeutics
- Laina Health
- Level 6
- LogTech
- MedaLink
- NanoCatalytics
- NanoPattern Technologies
- NaviStone
- Neuros
- Plankk
- Predactiv
- Qualifi
- Ready Set Surgical
- RTI
- Revenue Conduit/Unific
- RallyPoint
- Sense Neuro
- Shift Thermal
- 7signal
- SoLoFunds
- Sure Impact
- Tactile
- Taiga Data
- TeamCentral
- TPAstream
- Trinity Guardion
- Voxel
42 of 123 funded companies · IT · Life Sciences · Advanced Materials · See the full portfolio →
The People
215+ Greater Cincinnati leaders. Led by:
Former CEOs and founders who have operated, exited, and now invest — and mentor — together.
Member investors — former CEOs and founders across Greater Cincinnati — contributing 50,000+ member-hours annually. Individual members remain private; their work shows in the portfolio. Meet the leadership →
Beyond Capital
Education and counsel, built into the model.
Startup College®
Run by the QCA Education Foundation, a 501(c)(3). More than 1,000 entrepreneurs trained.
eKickstart
Early-stage guidance for founders preparing to raise and build.
QCA Morning Mentoring™
Direct working sessions with member operators and investors.
Entrepreneur Boot Camp
Intensive preparation for the realities of company building.
Membership
Regular membership (voting) for active angel investors, and the Ascent starter tier — from a $25,000 minimum commitment.







